NFL 2025 Week 16 Start 'Em Sit 'Em: Stack Brock Purdy and Jauan Jennings - NBC Sports
The 49ers' passing game is in a great spot versus the Colts this week. Brock Purdy is in line for QB1 numbers and should bring Jauan Jennings along for the ride as a potential WR2.
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NFL 2025 Week 16 Start ‘Em Sit ‘Em: Stack Brock Purdy and Jauan Jennings
By
Kyle Dvorchak,
By
Kyle Dvorchak
Published December 19, 2025 01:48 PM
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Thursday Night Football kicked off the fantasy football semi-finals with a bang. If you faced Puka Nacua, I hope these Starts help you claw your way back into the race. If Puka is on your squad, maybe some of my Sits will be in your opponent’s lineup.
Purdy was a big hit for me last week based on sportsbooks’ love of the 49ers. You won’t believe it, but Vegas is backing San Francisco once again. Their 26-point implied team total is the fourth-highest of the week. The Colts—their Week 16 matchup—rank 14th in pass EPA allowed and third in rush EPA. That disparity has led Colts opponents to record a +2% pass rate over expected, the third-highest mark in the league. Purdy should have volume on his side this week and his efficiency numbers speak for themselves.
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He is top-two in EPA per play and CPOE.
Sportsbooks are projecting a romp in Atlanta, with a 48.5
Rating: 5