Annette Dionne: Last of Canada's Dionne quintuplets dies aged 91

The sisters, who were the first known quintuplets to survive past infancy, became a global phenomenon after their 1934 birth.

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The five identical sisters, born in Ontario at the height of the Great Depression in 1934, were the first known quintuplets to survive past infancy.

They quickly became a global sensation during their childhood - starring in feature films, appearing on the covers of magazines, and endorsing products from toothpaste to syrup.

"Much beloved, Annette had championed children's rights," the museum said in a statement announcing her death.

The museum, which seeks to preserve their legacy and educate the public on the quintuplets' controversial upbringing, added: "She believed it was important to maintain the Dionne Quints Museum and the history it provides for the future of all children."