What to watch for in weight loss drugs in 2026: Price changes, GLP-1 pills and more

Long-defined by high prices, shortages and weekly injections, weight loss drugs including Wegovy and Zepbound are expected to be easier to access and afford.

Changes are coming in 2026 for GLP-1 drugs.

Long defined by high prices, shortages and weekly injections, drugs including Wegovy and Zepbound are expected to be easier to access and afford. And new options for people averse to needles are coming.

“The GLP-1 landscape is expected to broaden significantly,” said Dr. Christopher McGowan, a gastroenterologist who runs a weight loss clinic in Cary, North Carolina. “For the first time, medical obesity treatment will move away from a one-size-fits-all model.”

GLP-1 pills for weight loss may mark the most significant shift yet.

Last month, Novo Nordisk won Food and Drug Administration approval for the first GLP-1 pill for weight loss. The medication, marketed as the Wegovy pill, is expected to be widely available this month.